No. If maintenance does their job right. There’s no degradation, only failures of components. Once the fault has been identified and repaired, the system is 100% functional.
If things are failing, you get flat and blown tires.
Anti-Skid does exactly what its name states. It keeps the tires from skidding. All wheel speeds are monitored. If one has a wheel speed less that the others, it would be treated as a skid and the hydraulic pressure to that brake is reduced (or stopped) until the wheel speeds back up.
Pilots still apply brake pressure as they see fit. The Anti-Skid works without any input from them at all. On a 767 there is no Anti-Skid switch in the cockpit. It's always on.
If the aircraft has Auto-Brakes, it does everything and (not a good idea) the pilots wouldn't have to have their feet on the peddles at all.